First RNAi Therapeutic: In the Running for Science Magazine’s Breakthrough of 2018

ONPATTRO™, the first FDA approved siRNA therapeutic oligonucleotide duplex, has been highlighted by Science magazine as one of the most significant scientific breakthroughs of 2018. Read more about it and cast your vote for the People’s Choice for Breakthrough of the Year at the website below. Voting closes on December 12 at 11:59 PM EST.

 

More information: www.sciencemag.org/news/2018/12/finalists-are-vote-2018-people-s-choice-breakthrough-year?utm_source=6&utm_medium=social&utm_campaign=Science-%28ScienceMagazine%29&utm_term=SciMag&utm_content=AAAS&fbclid=IwAR1aTGlDBs75RkeCJ6aKpTZT4ojuFUCfJiuQaL0udDODuFx_CVbzRnapgzk

 

Hot Papers

The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold

Mary K. Yates, Katherine L. Seley-Radtke

Antiviral Research, Volume 154, 66-86

The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold

Mary K. Yates, Katherine L. Seley-Radtke

Antiviral Research, Volume 162, 5-21

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